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Description
Biotin Mouse Anti-Human CD200R Antibody (S-3128)Product Specification Host Mouse Antigen CD200R Synonyms Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1 Location Cell membrane Accession Q8TD46 Clone Number S 3128 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood Leukocytes Purification Protein G Concentration 0. 2 mg ml Conjugation
Product Specification
| Host | Mouse |
| Antigen | CD200R |
| Synonyms | Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1 |
| Location | Cell membrane |
| Accession | Q8TD46 |
| Clone Number | S-3128 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood Leukocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD200R is a trans-membrane glycoprotein of the immunoglobulin superfamily encoded by CD200R1, expressed chiefly on myeloid cells (macrophages, dendritic cells, microglia) and some lymphoid subsets; when engaged by its ligand CD200 (OX-2) it becomes tyrosine-phosphorylated in its cytoplasmic NPxY motif, recruits the adaptor Dok-2 and RasGAP, thereby dampening Ras/MAPK and NF-κB signaling to suppress production of TNF-α, interferons and iNOS, curb mast-cell degranulation, restrain ILC2 effector cytokines, and broadly down-regulate innate and adaptive inflammatory responses, a signaling axis that is exploited by tumors for immune evasion and is being therapeutically targeted to treat asthma, neuroinflammation and cancer .
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Exchange/Return Notes
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4.5 ★★★★★
Based on 1462 reviews
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Product Reviews
★★★★★ 4
Will buy again
Size: 25in, Style: Sport
Fits the bill.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2025
★★★★★ 5
Must Have for Tiring Out Your Pup
Size: 25in, Style: Sport
The Chuckit! Sport 25M Dog Ball Launcher is an absolute must-have for any dog owner with an active pup! This thing takes fetch to a whole new level—effortless long throws, hands-free pickup (no more slobbery tennis balls!), and a comfortable grip that makes playtime easier and way more fun.
My dog absolutely loves it, and I love that it helps her burn off energy without tiring out my arm. The included medium ball is the perfect size for medium to large dogs, and the durable construction means it's built to last. If you're looking for a simple but game-changing way to upgrade fetch, this is it. Highly recommend!
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Reviewed in the United States on February 13, 2025
★★★★★ 5
My Niece dog loves it!
Size: 18in, Style: Sport
This ball launcher takes a bit of getting. used to, but it is really helpful for those of us who are not MLB pitchers! The launcher itself is a sturdy plastic that is not brittle yet not soft; when the ball is launched there is no destructive bending in the shaft. The handle is padded and ergonomically sound while the cup end cradles the ball but has cut-outs on each side for easy loading and unloading of the ball. It did take a bit of practice for me to get the hang of it, but for my husband and son it was much easier. The launcher works well to help us older, non-gifted athletes launch the ball farther and faster while saving the shoulder, elbow, and wrist (important if there is any arthritis). The ball fits nicely into the cup and releases easily.
The 2.5 size was too small for my Doberman, so we opted for the 3.5 in launcher. This smaller launcher and ball are now in the employ of my sister and her husband for their retriever-border collie mix, an 18 month old little fireball!. This is just the right size for her. My sister's husband has difficulty with arthritis and is neither quick on his feet nor able to stand very long. So the launcher comes in very handy. He can actually sit in a lawn chair and throw the ball repeatedly when their dog retrieves and returns it to him. That is a win- win!
Top 3 Likes:
-Easy to use
-Helps older pet owner
-Drives the ball farther and faster
Top 3 Dislikes:
-With repeated uses the edges of the launcher appear to get scuffed and scratched
-Some ingrained staining on the edges persists requiring scrubbing to remove
-There is a mild worry that with time the launcher may snap
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Reviewed in the United States on September 4, 2024
★★★★★ 5
My dog loves it
Size: 25in, Style: Sport
I am amazed at how far I can throw a tennis ball. My dog and I absolutely love this. What happens to work well with the squeaky balls?I get on amazon as well. I have one of these at home, And I keep another one in the truck.
Very durable, The balls have good bounce, My dog and I have a lot of fun with it. My dog doesn't chew much on balls, But this one seems like it's going to stand out, I love the versatility, Hey can handle almost ending ball that same size. Are you solid rubber bouncy balls, Squeak.
Ing tuba balls, Whiffle balls with all the holes in it, Even the squeaky chewing balls. As long as there are that same size.
love the product. I've been using them for a few years.
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Reviewed in the United States on July 22, 2024
★★★★★ 5
Durable
Honestly I didn't think this ball would last but 2 years later and only one battery change later and it is going strong. This ball has given me so much more time to play with my dog since I can throw the ball at night on short winter days I can't recommend it enough. I can throw the ball at night and my dog can find it in the dark. Add a collar LED and it's a funny light show of one light intercepting another.
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Reviewed in the United States on February 26, 2026
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