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Description
IGF1 Receptor Recombinant Rabbit mAb (S-1617-146)Product Specification Host Rabbit Antigen IGF1 Receptor Synonyms Insulin like growth factor 1 receptor; Insulin like growth factor I receptor (IGF I receptor); CD221; IGF1R Immunogen Recombinant Protein Location Cell membrane Accession P08069 Clone Number S 1617 146 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample MCF7, A431, HepG2, HeLa, HCT 116, MDA MB 231, HEK 293, C2C12, NIH 3T3, mouse brain, mouse
Product Specification
| Host | Rabbit |
| Antigen | IGF1 Receptor |
| Synonyms | Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor (IGF-I receptor); CD221; IGF1R |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P08069 |
| Clone Number | S-1617-146 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | MCF7, A431, HepG2, HeLa, HCT 116, MDA-MB-231, HEK-293, C2C12, NIH/3T3, mouse brain, mouse spleen, C6, rat brain |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
Background
The insulin-like growth factor 1 receptor (IGF-1R) is a transmembrane receptor tyrosine kinase that is widely expressed on the surface of human cells and plays a crucial role in cell growth, proliferation, and differentiation. It is activated by insulin-like growth factor 1 (IGF-1) and IGF-2, and to a lesser extent by insulin. The IGF-1R is structurally similar to the insulin receptor and consists of two extracellular α-subunits involved in ligand binding and two transmembrane β-subunits containing a tyrosine kinase domain. Upon activation, IGF-1R triggers several intracellular signaling pathways, including the PI3K/Akt/mTOR and RAS/RAF/MAPK pathways, which promote cell survival, inhibit apoptosis, and regulate metabolism. Additionally, IGF-1R has been found to migrate to the cell nucleus, where it can act as a transcriptional activator. Given its significant anti-apoptotic and pro-survival functions, IGF-1R is highly expressed in many types of cancer and is considered a promising target for cancer therapy.
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4.2 ★★★★★
Based on 162 reviews
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Product Reviews
★★★★★ 5
Best vanilla body wash I've seen
Proper vanilla scent with a kick, without the vomit inducing synthetic aftertaste
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
★★★★★ 5
Cremo Bourbon & Oak 2-in-1: A Gentleman's Shower Staple
Scent: Bourbon & Oak, Size: 16 Fl Oz (Pack of 1)
The Cremo Bourbon & Oak 2-in-1 Shampoo & Conditioner isn't just a cleaning product; it's an experience. In a world of sterile, generic men's grooming, Cremo consistently delivers a distinctive, high-quality product that feels far more premium than its price tag suggests. If you're looking to elevate your daily shower ritual, this is the bottle to grab.
The Scent: Unmistakable Sophistication
The most immediate and defining characteristic of this product is, without a doubt, its Bourbon & Oak fragrance. It masterfully blends warm, slightly sweet notes of aged oak and barrel-aged bourbon with a subtle, earthy musk.
Projection: The scent is robust in the shower, creating a satisfying, rich steam, but it quickly settles down. It leaves a subtle, masculine residual scent on your hair that lasts for hours without overpowering cologne. It smells authentic—like a high-end barbershop mixed with a cozy speakeasy.
Aroma Profile: Unlike many cheap fragrances that smell synthetic, the Cremo scent is layered and complex, avoiding that cloying sweetness that can plague other vanilla or wood-based products.
Performance: The Best of Both Worlds
When it comes to 2-in-1 products, there's always a risk of compromise—great cleaning, poor conditioning, or vice versa. Cremo successfully sidesteps this pitfall.
Cleansing Power: The shampoo produces a rich, satisfying lather that effectively cuts through product buildup and oil without stripping the hair of its natural moisture. It leaves the scalp feeling invigorated and genuinely clean.
Conditioning Efficacy: This is where the product truly shines. After rinsing, the hair feels surprisingly soft and manageable. For men with shorter to medium-length hair, the built-in conditioner provides enough hydration to prevent that stiff, straw-like feeling that often follows a wash. It makes combing and styling noticeably easier.
Formula: It’s formulated to rinse clean with no residue, which is essential for a product designed for daily use.
The Verdict
The Cremo Bourbon & Oak 2-in1 is an exceptional offering that delivers on its promises. It is the gold standard for men who want a convenient, high-performing 2-in-1 without sacrificing the luxury of a refined scent.
Final Recommendation: Buy it. This is an easy replacement for whatever generic shampoo you currently have in your shower. It’s an effortless way to upgrade your routine and start your day with a confidence-boosting aroma.
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Reviewed in the United States on October 10, 2025
★★★★★ 5
5/5
Scent: Palo Santo, Size: 16 Fl Oz (Pack of 1)
absolutely love the Palo Santo Chemo Body Wash by Cremo. The scent is warm, woodsy, and slightly sweet without being overpowering. It smells clean but elevated — like a subtle, high-end cologne that lingers just enough after you shower.
The lather is rich and creamy, and a small amount goes a long way. It leaves my skin feeling clean and moisturized without that tight, dry feeling some body washes cause. The fragrance lasts for hours, which I appreciate because it layers well with other products.
If you like warm, earthy scents with depth, this is a must-try. I will definitely be repurchasing!
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Reviewed in the United States on February 24, 2026
★★★★★ 5
Nice body care need not cost a fortune.
Scent: Palo Santo, Size: 16 Fl Oz (Pack of 1)
The Cremo product line is a favorite and Palo Santo is one that tops the list for us. We like the Cremo body care line's execution, variety, quality, anti- elitist price and inclusive availability. Palo Santo is softly sweet with just enough cardamom spice and papyrus for a round, smooth aroma with no sharp edges to annoy those around you. Just enough of the Cremo body wash frangrance lingers to keep you feeling fresh all day. This product lathers nicely and is neither too heavy nor too thin to use with a traditional wash cloth, loofah, natural or synthetic sponge, pouf or bath brush. Cremo body wash makes a nice foot soak and hand wash too. We fill a bottle to keep by the kitchen and bathroom sinks. Our wish is that the company produces large, minimally packaged refills to spare the plastic. Until then, please reuse and / or recycle the containers. NOTE: When selecting fragrance, ignore marketing and wear what appeals to you. Treat gender, age, price category snobbery and other target market gimmicks as irrelevant. Wear / use what you like, and not because it is purported to be "exclusive", someone told you to or that you cannot possibly be cool / alluring / beautiful / handsome or appear wealthy or celebrity-adjacent without it.
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Reviewed in the United States on May 25, 2026
★★★★★ 5
Add to Cart ❤️
Scent: Bourbon & Oak, Size: 16 Fl Oz (Pack of 1)
The scent is incredible — warm, slightly sweet bourbon with a rich oak finish. It smells high-end without being overpowering. It lingers just enough to notice but doesn’t clash with cologne.
Performance-wise, it delivers. It cleans thoroughly without stripping and leaves hair soft and manageable instead of dry or heavy. For a 2-in-1, it actually conditions well — which isn’t always the case with combo products.
I originally bought it as part of a gift set for my father, and he’s since had me repurchase it four times — so that says everything.
If you like warm, masculine, slightly woody scents and want something that performs as good as it smells, this one truly hits the ball on the head. Definitely a repeat buy.
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Reviewed in the United States on February 28, 2026
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