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Description
Runx2 Recombinant Rabbit mAb (S-1767-173)Product Specification Host Rabbit Antigen Runx2 Synonyms Runt related transcription factor 2; Acute myeloid leukemia 3 protein; Core binding factor subunit alpha 1 (CBF alpha 1); Oncogene AML 3; Osteoblast specific transcription factor 2 (OSF 2); Polyomavirus enhancer binding protein 2 alpha A subunit (PEA2 alpha A; PEBP2 alpha A); AML3; CBFA1; OSF2; PEBP2A Immunogen Recombinant Protein Location Cytoplasm, Nucleus Accession Q13950 Clone Number S 1767
Product Specification
| Host | Rabbit |
| Antigen | Runx2 |
| Synonyms | Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1 (CBF-alpha-1); Oncogene AML-3; Osteoblast-specific transcription factor 2 (OSF-2); Polyomavirus enhancer-binding protein 2 alpha A subunit (PEA2-alpha A; PEBP2-alpha A); AML3; CBFA1; OSF2; PEBP2A |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus |
| Accession | Q13950 |
| Clone Number | S-1767-173 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | Saos-2, PC-3, MDA-MB-231, C2C12 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:500 | Hu, Ms, Rt |
| ICC | 1:500 | Hu, Ms |
Background
Runx2, also known as Runt-related transcription factor 2, is a crucial transcription factor for bone development and plays a key role in the regulation of osteoblast differentiation and skeletal morphogenesis. It is expressed in prehypertrophic and hypertrophic chondrocytes, and its mutation can lead to skeletal malformation syndromes such as cleidocranial dysplasia. Runx2 induces chondrocyte maturation and proliferation through the regulation of various signaling pathways, including Indian hedgehog (Ihh) and vascular endothelial growth factor A (Vegfa). In addition to its role in normal bone development, Runx2 is also involved in pathological conditions such as breast cancer metastasis and lung fibrosis.
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4.5 ★★★★★
Based on 1475 reviews
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Product Reviews
★★★★★ 5
Love!
Style: Kids SPF 50, Size: 5 Fl Oz (Pack of 1)
This is the best smelling sun screen ever!! It sprays so smooth as well!! My kids sensitive skin takes to it! It’s not cold and the coverage is great!! Also love that HSA available
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Reviewed in the United States on September 9, 2024
★★★★★ 5
Reliable protection that stays put during workouts!
Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
I’ve tried many expensive name-brand sunscreens, but this Amazon Basics version performs just as well, if not better. It’s become my go-to for morning runs and trips to the beach because it actually stays on even when I’m sweating.
Why I gave it 5 stars:
Non-Greasy Formula: Unlike other sport sunscreens, this one absorbs quickly and doesn't leave that heavy, sticky film on my skin.
Actually Water Resistant: I’ve used it for laps in the pool and long hikes; as long as I reapply as directed, I haven't had a single sunburn.
No "Sting": One of the best things is that it doesn't run into my eyes and sting when I start to sweat—a huge plus for runners.
Great Value: You get a generous 8-ounce bottle for a fraction of the price of "premium" brands. The fact that it’s formulated without Oxybenzone is an added bonus for peace of mind.
If you’re looking for effective, no-frills sun protection for an active lifestyle, you can't beat this. It’s a staple in my gym bag now!
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Reviewed in the United States on April 6, 2026
★★★★★ 5
Great value and very practical
Style: SPF 50, Size: 8 Fl Oz (Pack of 6)
This sunscreen is a great value for the price. The SPF 50 protection works well and the lotion applies smoothly without feeling too greasy. It absorbs nicely and provides good coverage for outdoor activities.
I especially like using these bottles to refill the sunscreen dispensers at my Airbnb for guests. It’s convenient, reliable, and affordable when you need multiple bottles available.
Overall, it’s a solid everyday sunscreen and a very practical option if you need good protection at a reasonable price.
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Reviewed in the United States on March 11, 2026
★★★★★ 4
good price for good product. applies well, shake and store upright
Style: SPF 50, Size: 8 Fl Oz (Pack of 1), Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
I believe it is equal to the name brands
It is 50 SPF Sun Protection Factor so it offers strong UV A and UV B protection which are the 2 ranges of sun rays that do the skin damage and burning.
It is an easily absorbed lotion that when rubbed goes into the skin and is not visible. It is thick and goes on with a non shiny, non greasy, solid thick feeling which is what we need for it to stay on as long as possible.
It feels good after being rubbed in in that it feels dry and not overly greasy or with no shine and sheen.
It is a good product and offers burn protection to me in some clear-sky strong sun uses.
Reapply after entering the pool water or swimming laps and after an hour (all sunscreen labels say reapply after 80 minutes which I believe is per recommendations of the federal FDA or some medical studies).
I reapply often and I still get tanned but I do not want to burn.
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Reviewed in the United States on August 9, 2025
★★★★★ 5
Survived the sun like a pasty legend
Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
I bought this sunscreen because I’m basically a human marshmallow — one hour in the sun and I’m toasted. This Amazon Basics Sport SPF 50? It’s like armor for the pale and easily crisped. I slathered it on before a full day of hiking, sweating, and pretending I enjoy direct sunlight, and guess what? No burn. Not even a pink glow. Just victory.
It goes on smooth, doesn’t feel greasy, and somehow stayed put through sweat, water, and my dog licking my arm. It’s fragrance-free, which means I didn’t smell like a coconut smoothie or a chemical spill — just clean and protected.
Pros:
• High SPF that actually works
• Sweat and water resistant — like, impressively so
• No greasy residue or weird smell
• Affordable and comes in a big ol’ bottle
• Didn’t turn me into a lobster (the bar is low, but still)
Minor feedback:
It’s not fancy or trendy, but honestly, I’m here to not burn — not win a skincare award. Also, it takes a bit of rubbing in, but once it’s on, it’s locked and loaded.
Final thoughts:
If you want solid sun protection without the drama, this stuff delivers. Whether you’re hiking, swimming, or just trying to survive summer, it’s a reliable sidekick. Would absolutely buy again — my skin demands it.
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Reviewed in the United States on November 7, 2025