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Description
Alexa Fluor® 647 Armenian hamster Anti-Mouse CD196 Antibody (S-R621)Product Specification Host Armenian hamster Antigen Mouse CD196 Synonyms C C chemokine receptor type 6; C C CKR 6; CC CKR 6; CCR 6; KY411; Ccr6; Cmkbr6 Location Cell membrane Accession O54689 Clone Number S R621 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 05mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25%
Product Specification
| Host | Armenian hamster |
| Antigen | Mouse CD196 |
| Synonyms | C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; KY411; Ccr6; Cmkbr6 |
| Location | Cell membrane |
| Accession | O54689 |
| Clone Number | S-R621 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD196, also known as CCR6, is a seven-transmembrane, G-protein-coupled receptor that belongs to the beta chemokine receptor family. It is predominantly expressed on B lymphocytes, certain subsets of effector and memory T cells, and immature dendritic cells. CCR6 is a receptor for the CC chemokine CCL20 and also binds with lower affinity to beta-defensin 2. This receptor plays a crucial role in mediating the trafficking of immune cells to epithelial sites near the skin and mucosal surfaces during inflammatory and immunological responses.
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4.4 ★★★★★
Based on 2423 reviews
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Product Reviews
★★★★★ 5
Flavored Dog Rubber Balls
Color: H) 2.5" 3-Pack (Beef), Color: H) 2.5" 3-Pack (Beef)
My dog absolutely loves these balls, I have a few more I had already bought, but she has an addiction to them so I had to buy more. I am able to squeeze these really easily so when she does pick them up after I’ve thrown them they’re very easy for her to pick up. They have a good thickness to them so it’s not too flimsy. It’s pretty tough and they bounce pretty high which I like and so does she know she is an aggressive chewer, but I haven’t had an issue yet with her chewing right through these, which is why I like them and we both love the fact that it smells like beef I could practically smell them through the bag, but I have a really high pitched sense of smell, and I knew she was going to love them. Not to mention you can’t beat the price.
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Reviewed in the United States on November 14, 2025
★★★★★ 5
Love These Balls
Color: H) 2.5" 3-Pack (Beef), Color: H) 2.5" 3-Pack (Beef)
These are great balls. My Border Collie can destroy a tennis ball in a couple of hours and the Kong brand ball is heavier than I like to play with in the house. These balls hold up to her biting and chewing but are lite weight and softer for bouncing off the walls.
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Reviewed in the United States on May 7, 2026
★★★★★ 3
Seems durable - but the scent is not the best
Color: B) 3" 2-Pack (Bacon)
I don't know if I'd call the scent of this "bacon," more like rubber with a hint of bacon. It's very strong. I gave my dog one of the balls & put one in a cabinet where I keep his treats & a few other unrelated odds & ends. I now hold my breath when I open that cabinet b/c good lord, the smell. I'm tempted to just give that one to the dog too, just because it'll air out eventually & then everything else in that cabinet won't smell bad.
My dog feels so-so about it. He'll briefly chase after it & chew on it, but loses interest in it pretty fast. My rather hyperactive cat also plays with it from time to time, as he seems to have more interest in most dog toys than the dog these days, so there's that. (Then again, he thinks a wide variety of random items around the house are loads of fun to toss about, so it's possible his opinion is to be taken with a grain of salt. Between the brief periods of one of these balls being chewed on & clawed at, it's stayed completely intact. I think if you have a dog who simply likes to play fetch or chew on rubber balls in general, this one would stand up to the task. But if you're expecting it to be greeted with the enthusiasm as a bacon grease covered ball might be - I'd adjust your expectations.
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Reviewed in the United States on February 19, 2023
★★★★★ 5
My dogs favorite toy so far in two years
Color: C) 4" 2-Pack (Bacon)
I use this with my medium sized dog. These are large for him but that's what I want so I don't ever have to think about them being too small or a swallow hazard. He has been through A LOT OF TOYS in the last couple years, but nothing, NOTHING has he loved as much as these.
His favorite used to be squeaker balls. Then his favorite was crackle balls. But he will gladly ignore both for this one. I don't know if it's the bacon flavor or what, but he go nuts for it.
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Reviewed in the United States on May 5, 2026
★★★★★ 5
Bacon? IDK but good stuff either way
Color: C) 4" 2-Pack (Bacon)
What is there to say? they're giant 4" rubber balls from the Chew King brand which is very durable brand. The best part is they don't roll under couches, side boards, etc cause they're just big enough.
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Reviewed in the United States on April 24, 2026