Alexa Fluor® 488 Rat Anti-Mouse IgD Antibody (S-R622)
SKU: 34814782148

Alexa Fluor® 488 Rat Anti-Mouse IgD Antibody (S-R622)

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Description

Alexa Fluor® 488 Rat Anti-Mouse IgD Antibody (S-R622)Product Specification Host Rat Antigen IgD Synonyms Ig delta chain C region membrane bound form Location Cell membrane Accession P01882 Clone Number S R622 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date

Product Specification


Host Rat
Antigen IgD
Synonyms Ig delta chain C region membrane-bound form
Location Cell membrane
Accession P01882
Clone Number S-R622
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

IgD is a monomeric antibody isotype that, in humans, is primarily co-expressed with IgM on the surface of naïve B cells where it functions as an antigen receptor whose cytoplasmic tail participates in B-cell receptor signaling to modulate activation, survival, and differentiation; although it constitutes only about 0.25 % of serum immunoglobulin, secreted IgD appears to bind basophils and mast cells via galectin-9 to promote antimicrobial and inflammatory responses at mucosal surfaces, while its heavy chain constant region contains three immunoglobulin-like domains and undergoes extensive alternative splicing and class-switch recombination that together provide evolutionary flexibility and fine-tuned regulation of immune responses.

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SKU: 34814782148

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